Sitagliptin Phosphate and Metformin Hydrochloride Tablets

Sitagliptin Phosphate and Metformin Hydrochloride Tablets


Sitagliptin Phosphate and Metformin Hydrochloride Tablets come under the brand name “ALOSIT M” and is a combination medicine used to treat Type 2 diabetes. This condition occurs when the body either doesn’t produce enough insulin (the hormone that lowers blood sugar) or the insulin doesn’t work effectively. As a result, the body makes a lot of insulin, but it doesn’t properly affect the organs.

Sitagliptin Phosphate is a type of medicine called DPP-4 inhibitors. It helps lower high blood sugar levels by increasing certain natural substances in the body. On the other hand, Metformin Hydrochloride is a type of medicine called biguanides. It reduces the liver’s glucose production, slows down glucose absorption from the intestines, and makes the body more responsive to insulin. When these two medicines are used together, they prevent blood sugar levels from getting too high after meals.

Medical Benefits

  • It helps your pancreas produce more insulin and makes insulin work better in your body.
  • It also reduces the extra sugar made by your liver.
  • This medicine is important because it controls the rise of blood sugar after meals.
  • The best part is that it does not cause weight gain, even when used for a long time.
  • Using Sitagliptin Phosphate and Metformin Hydrochloride Tablets is crucial in controlling blood sugar levels and preventing serious complications of diabetes, such as loss of eyesight, kidney problems, nerve damage, diabetic foot ulcers, and slow wound healing.

Directions For Use

  • Take it with or without food as advised by the doctor.
  • Swallow it as a whole with a glass of water.
  • Do not break, crush or chew it.
  • Please take Sitagliptin Phosphate and Metformin Hydrochloride Tablets in the dose and duration prescribed by your doctor based on specific medical conditions.


  • Keep it away from sunlight.
  • Keep out of the reach of children.
  • Store in a cool and dry place.


  • It is best to avoid alcohol while taking medication.
  • Before taking this medicine you must be well-known that it interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), and many more drugs.
  • People affected with heart diseases, Vitamin B12 deficiency, and alcoholism should avoid intake of Sitagliptin Phosphate and Metformin Hydrochloride Tablets.
  • These tablets are only recommended during pregnancy when the benefit outweighs the risk. Please consult your doctor before starting medication.

Side Effects

  • Runny nose
  • Sore throat
  • Upper lung infection
  • Diarrhoea
  • Nausea

Frequently Asked Questions ( FAQs)

How will I know that I am suffering from diabetes?

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact your doctor as it can be a condition of type 2 diabetes.

How will I know that I have lactic acidosis?

Lactic acidosis is a rare but life-threatening condition when there is too much lactic acid buildup in the bloodstream. Long-term intake of this tablet may lead to lactic acidosis when cells get deprived of oxygen levels. Symptoms of lactic acidosis include a burning sensation in muscles, muscle aches, fast breathing, nausea, and stomach pain. Immediately contact the doctor about this complication.

If my blood sugar level suddenly goes down, then what should I do?

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

Can I take alcohol with it?

Do not take excessive alcohol while taking this medicine, as this may increase the risk of a life-threatening condition called lactic acidosis (too much lactic acid in the body).

Is this composition also prescribed for the treatment of type 1 diabetes?

No, it is only prescribed for the treatment of type 2 diabetes also called as ‘non-insulin-dependent diabetes’.


Alosit M


Sitagliptin Phosphate & Metformin Hydrochloride Tablets 50mg, 500mg


10 X 15