Description
Amoxicillin/Clavulanic acid is an antibiotic and works by killing bacteria that cause infections. Amoxicillin belongs to a group of medicines called “penicillins” that can sometimes be stopped from working (made inactive) & clavulanic acid stops this from happening. This medication is most commonly used to treat infections of the sinus, ear, lung, skin, and bladder.
DOSAGE
1 tablet once a day.
INDICATIONS
Upper Respiratory Tract Infections (including ENT): e.g. tonsillitis, sinusitis, otitis media
Lower Respiratory Tract Infections: e.g. acute exacerbations of chronic bronchitis, lobar and broncho- pneumonia
Genito-urinary Tract Infections: e.g. cystitis, urethritis, pyelonephritis, female genital infections
Skin and Soft Tissue Infections
Bone and Joint Infections: e.g. osteomyelitis
Other Infections: e.g. septic abortion, puerperal sepsis, intra-abdominal sepsis, septicaemia, peritonitis, post-surgical infections
SIDE EFFECTS
• abdominal and stomach cramps
• bad taste in mouth
• constipation
• diaper rash (infant)
• diarrhea (mild)
• gas
• headache
• loss of appetite
• nausea
• unusual tiredness or weakness
• vomiting
DRUG INTERACTIONS
Probenecid decreases the renal tubular secretion of amoxicillin. Concurrent use with amoxicillin and clavulanate potassium may result in increased and prolonged blood levels of amoxicillin. Co-administration of probenecid cannot be recommended.
The concurrent administration of allopurinol and ampicillin increases substantially the incidence of rashes in patients receiving both drugs as compared to patients receiving ampicillin alone. It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients. There are no data with amoxicillin and clavulanate potassium and allopurinol administered concurrently.
In common with other broad-spectrum antibiotics, amoxicillin and clavulanate potassium may reduce the efficacy of oral contraceptives.
