Description
Levofloxacin possesses a broad spectrum of activity against many common pathogens and attains exceptionally high intracellular and tissue levels following oral administration. The bactericidal effect of levofloxacin is concentration-dependent. This means that if the dose is increased, it is possible to increase peak concentration, which is associated with even better tissue concentration and a possible reduction in the development of resistance. High-dose levofloxacin provides an effective treatment for severe infections by exploiting these pharmacokinetic features.
DOSAGE
1 tablet once a day
INDICATIONS
Acute exacerbations of chronic bronchitis, Pneumonia (community acquired), Sinusitis, Urinary tract infections (complicated) and acute pyelonephritis, Uncomplicated urinary tract infections in women, Skin and soft tissue infections (uncomplicated), Skin and soft tissue infections (complicated), Intra-abdominal infections.
SIDE EFFECTS
The most common side effects of Levofloxacin are:
• Nausea
• Headache
• Diarrhea
• Insomnia
• Constipation
• Dizziness
DRUG INTERACTIONS
Do not take this medicine with any of the following medications:
• Arsenic trioxide, chloroquine, droperidol, medicines for irregular heart rhythm like amiodarone, disopyramide, dofetilide, flecainide, quinidine, procainamide, sotalol, some medicines for depression or mental problems like phenothiazines, pimozide, and ziprasidone
This medicine may also interact with the following medications:
• Amoxapine, antacids, birth control pills, cisapride, dairy products, didanosine buffered tablets or powder, haloperidol, multivitamins, NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen, retinoid products like tretinoin or isotretinoin, risperidone, some other antibiotics like clarithromycin or erythromycin, sucralfate, theophylline, warfarin.
